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4.3 Heme oxygenase-1 (HO-1, also known as HSP32) Increased HO-1 levels may cause an excessive accumulation of iron and carbon monoxide, resulting in oxidative stress and cellular damage

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The liver generates glutathione in reduced amounts

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Transplantation of Apoe -/- mice with wildtype bone marrow, resulted in normalization of plasma cholesterol levels and protection from atherosclerosis (99), demonstrating the ability of macrophage apoE to exchange between lipoproteins and to serve as a vehicle for cellular gene therapy of atherosclerosis

van der SluisPCvan der HorstSMayLSpillenaar BilgenEJBonsingBABosschaKet alRobot-assisted minimally invasive thoracolaparoscopic esophagectomy versus open transthoracic esophagectomy for resectable esophageal cancer: a randomized controlled trial