Weight regain after discontinuation is nearly universal without sustained lifestyle changes
LAC, @ HOU, @ OKC Last Week:19 Record: 31-31 OffRtg: 113.6 (17) DefRtg: 113.6 (14) NetRtg: -0.0 (18) Pace: 103.0 (3) The Hawks have taken advantage of a soft and home-heavy stretch of schedule (that isnt over yet) to win four straight games (by an average of 24 points) and climb to .500 for the first time since they were 15-15 just before Christmas
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Combining with other weight loss agents Tesofensine + GLP-1 agonists (theoretical): Different mechanisms = potential synergy Tesofensine: Metabolic + CNS appetite GLP-1s : Strong appetite + gastric slowing Could enhance weight loss to 20-25%+ BUT: No clinical data, significant risks Not recommended without supervision Potential combination benefits: Address multiple pathways Overcome plateaus Better than either alone (theoretically) Metabolic boost + strong appetite suppression Maximum fat loss Combination risks: Compounded cardiovascular strain Unknown drug interactions Excessive weight loss risks Cost ($1,500-2,000/month) Safer alternatives to tesofensine combinations: Tirzepatide alone (15-22% loss, FDA approved) CagriSema (sema + cagrilintide, 15-25%) GLP-1 + lifestyle (safer, proven) Learn about peptide stacking strategies at SeekPeptides
We considered that a consensus was reached when the lower bound of the 95%confidence intervals is 50% or higher
Useful indication Researchers are also recognizing that elevated B12 may not be a cause of cancer, but it could be a useful marker of whether cancer is present or progressing