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Various carcinoma tissues, including nasopharyngeal 21 , breast 22 , ovary 22 , and colorectal carcinomas 22,23 are reported to host commensal microbes that form unique cancer microbiota that could potentially impact the carcinogenesis, progression, and treatment of the host tumor cells 24,25

This illustrated that the PARK2 knockout model mimicked some biochemical alternations seen in PD 5,36,40 and associated with pathological processes such as inflammation and oxidative stress 36,37

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doi: 10.1176/appi.ajp.20231063 York Jesse

17 Because phosphatidylcholine is also protective to cholangiocyte epithelium, MDR3 dysfunction permits bile acidmediated hepatocyte damage, which, if chronic, is associated with an increased risk of progression to secondary sclerosing cholangitis or biliary cirrhosis

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