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AHK-Cu significantly stimulates vascular endothelial growth factor (VEGF), a key driver of angiogenesis, or the formation of new capillaries that deliver oxygen and nutrients to dermal tissue

That is an important framing for anyone tempted to treat it as a shortcut: even in the animal work that generates the interest, the compound is one input alongside energy balance, not a replacement for it

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It comes down to designing a dosing schedule that respects the compound's kinetics

In rare cases, starting high-dose B12 treatments for severe anemia may cause temporary imbalances in potassium levels or an acne-like rash