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Using SynGO 35 to screen the DEPs in Akap11 -cKO mouse and AKAP11 -KO iNeuron, we found an enrichment in both pre- and postsynaptic compartments, sharing multiple sub-synaptic terms, including regulation of synapse assembly, SV exocytosis and endocytosis, postsynaptic membrane neurotransmitter receptor levels, and chemical synaptic transmission (Supplementary Fig

Rouette A, Trofimov A, Haberl D, Boucher G, Lavalle VP, DAngelo G, et al

This gives them more control over their treatment

SCD1: Stearoyl-CoA desaturase 1

PMID 14482007

The mechanism appears to involve changes in how skin bacteria produce porphyrins, compounds that can promote inflammation within hair follicles