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In addition, the intervention of Chinese medicines on ferroptosis has been shown to be more stable and safer to use compared with small-molecule inducers or inhibitors of ferroptosis (185)

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Several studies have questioned the efficacy of immunoglobulin treatment, which is not recommended in the 2016 UK guidelines for the management of EN.4 A recent Spanish study6 (n = 49) reported an increase in survival in patients treated with cyclosporine

This problem has been addressed by stressing the need for a hybrid approach blending evidence- and consensus-based processes for recommendations regarding inborn errors of metabolism

Components can vary from clinic to clinic

Targeting glutamine metabolism rescues mice from late-stage cerebral malaria