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124 Treatment of rats with an ethanol extract of Epimedium koreanum Nakai (0.7 g/kg) for 28 days caused metabolic changes and mild liver injury

Elevated levels of 4-HNE covalently modify scaffold proteins such as GM130 and GRASP65, resulting in Golgi stack disassembly and fragmentation

doi: 10.1016/j.celrep.2018.08.002 74 KalevPHyerMLGrossSKonteatisZChenCCFletcherMet al

ROS and Malondialdehyde (MDA) Contents Liver tissues (50 mg) were homogenized by adding 40 mM Tris-HCl buffer and centrifuged (12,000 g , 10 min, 4 C)