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The gut-liver axis becomes pathologically altered in NAFLD due to increased intestinal permeability, enabling translocation of microbial products into the liver and exacerbating inflammation

R.CarpenterW.DuckworthK.et al (2014)

Through thick and thin: wasting, obesity, and TNF alpha

L., and Lau, F

After 72 h, the sites of the brown area were assessed using a chromameter (CR-400, Konica Minolta, Japan), and the degree of discoloration with the sample applied twice a day was measured every day