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Quick Answer: Original Russian protocol: 5 to 10 mg SC daily for 10 to 20 days, 2 to 4 cycles per year Total annual exposure under these protocols ranges from roughly 100 mg (5 mg x 10 days x 2 courses) to 800 mg (10 mg x 20 days x 4 courses)

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By week 12, most users on the combination report 15 to 20 percent body weight reduction

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While this is easy to interpret (it is the fraction of radioligand bound to receptors), an alternative is to express specific binding in sites/cell or fmol/mg protein, and to express the free radioligand concentration in nM