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Oxeiptosis is mediated by KEAP1, phosphoglycerate mutase family member 5, and apoptosis-inducing factor mitochondrion-associated 1 under oxidative stress [6]

A diet high in processed and refined foods, including refined carbohydrates and added sugars, has been linked to an increased risk of UFs [43]

The Fe atom within active aconitase coordinates with oxygen atoms of citrate and water and acts as a Lewis acid to activate the hydroxyl group of citrate to facilitate the isomerization reaction

Through the regulation of these processes, SIRTs have been linked to longevity in organisms such as C

In fact, as we are living the era of precision medicine, there is a pressing need to identify high-risk workers, establish robust exposure-effect relationships, and develop targeted interventions to mitigate occupational cancer risk 36

Despite the high prevalence of nutritional deficits in this population, dietary guidance remains inconsistent across clinical practice