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Neuromology 14 , 114 (2012)

[DOI] [PMC free article] [PubMed] [Google Scholar] 232.Kovari A

Epithalon has been extensively evaluated in aging-prone and cancer-prone rodent models, where it has been shown to reduce spontaneous tumor formation, suppress oncogene expression (notably HER-2/neu), and increase median and maximal lifespan 1,2

This ability to reach the brain directly allows sulforaphane to potentially exert its protective effects at the cellular level, influencing brain function and neural pathways

Promotion of epithelial-mesenchymal transformation by hepatocellular carcinoma-educated macrophages through Wnt2b/-catenin/c-Myc signaling and reprogramming glycolysis