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Aging Cell 23 (4), e14093

If that sounds vaguely familiar, its because CPS 1 is the green light enzyme for the urea cycle

RET refers to a process where electrons flow in the opposite direction along the electron transport chain (ETC) compared with the typical oxidative phosphorylation process, leading to the generation of substantial amounts of ROS

Studies with methodological ambiguities, insufficient experimental clarity, or conflicting results were excluded from the final synthesis to preserve the scientific integrity of the review

There is also considerable evidence of a role for carbon monoxide in glaucoma (Stagni et al., 2009)

J.OgunladeV.KuhlaB.Kientsch-EngelR.StahlP.WebsterJ.et al (2005)