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Symptoms of B12 Overload Though rare, extreme excess may cause: Itchy, inflamed scalp Acne or folliculitis Anxiety/insomnia (indirectly worsening hair loss) Gastrointestinal distress Managing High B12-Related Hair Loss 1

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Processes of Bone Elongation Endochondral Ossification and Growth Plate Morphology The skeleton develops by means of two different mechanisms: (1) Intramembranous ossification, involving direct differentiation of mesenchyme cells to bone as with the development of the flat bones of the skull and (2) Endochondral ossification, occurring when mesenchyme cells condense and differentiate into cartilage tissue, which then is replaced by bone forming the vertebrae, ribs and limbs [5]