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Animal studies suggest that NAC may help slow the progression of cognitive decline in individuals with Alzheimer's disease

Clin Cancer Res 2015

[11] As the condition progresses, the immune system response becomes increasingly dysfunctional

Based on this hypothesis and our previous work 10 , we tested in this study the combinatory killing effects of BSO, a potent specific inhibitor of GCL in glutathione biosynthesis 27 , and DPI, a widely used NOX inhibitor 28 , on HRAS G12V -transformed ovarian epithelial cells, mutant KRAS- bearing pancreatic and colon cancer cells, and murine pancreatic cancer cells harboring both KRAS and p53 mutations