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Burns et al., Figure 1), takes place in the nervous tissue affected by ischemia (Amantea et al., 2016), its absence causes ATP depletion within only a few minutes, which is the result of no long-term energy stores in the brain (Doyle et al., + ) and Ca 2+ into the cell, accompanied by potassium ion (K + ) efflux

Later, Hornig and colleagues also suggested disturbed IL-1 signaling and autoimmunity-type patterns of immune activation while analyzing the cerebrospinal fluid in patients with atypical clinical characteristics (Hornig et al

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Arthritis Rheum (2008) 58:387383

Previous research revealed that NADPH oxidase 4 (NOX4), a source of cellular superoxide anions, induces FAO through carnitine palmitoyltransferase 1A (CPT1A) during NLR family pyrin domain-containing 3 (NLRP3) inflammasome activation and helps in the development of the inflammatory macrophage phenotype (76)

doi: 10.1038/s41598-023-40011-0 46 AlemannoFHoudayerEParmaASpinaADel FornoAScatoliniAet al