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In its May 2026 public notice, the CDSCO made a definitive legal clarification under the Drugs and Cosmetics Act, 1940: products supplied in injectable form do not qualify as cosmetics under Indian law and cannot be marketed or used as such

Avoid caffeine and alcohol since these cause the body to remove fluid

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Some anecdotal reports of transient headache or mild nausea at higher doses

Because of the wide range of molecules that can trigger the induction of HMOX1 expression, the complete network of gene regulation leading to HMOX1 expression is not yet fully understood