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Np63 regulates serine biosynthesis and carboplatin resistance Given that serine levels in LUSC are significantly higher than that in LUAD, this suggests that serine biosynthesis might be activated in LUSC

These additional processes are known as posttranslational modifications

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Across these areas, the group seeks to decode the spatial logic and cellular language of tumor ecosystemshow diverse cell states, functional programs, and tumorimmunestroma interactions are organized across space and time into functional niches, cellular communities, and spatial archetypes that shape disease progression and clinical outcomes

This process requires meticulous surveillance of adverse events throughout clinical trials and comprehensive safety verification for each individual strain (563)