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Dries D, Yu G

The first reported observation that GTPases influence eryptosis was by Attanzio et al., who showed that NSC23766, a specific inhibitor of Rac1 GTPase, was able to ameliorate oxysterol-induced eryptosis [180]

Code availability Python scripts for automated image analysis are available on References Meister, A

It is conceivable that all or part of the adaptive response is broken or defective early in the disease process or becomes insufficient due to age-related decline in GSH levels [16]

Glutathione plays a key role in protecting the liver from damage caused by alcohol, drugs, and environmental toxins

In contrast to other GPxs, GPx4 is the only one that reduces the hydroperoxides of lipoproteins and complex lipids, such as cholesterol, cholesterol esters, and phospholipids [108], to protect mitochondrial ATP generation from oxidative damage [109]