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Thus, copper bound to the mitogen-activated protein kinase kinase 1 (MEK1) enhances its phosphorylation, thereby promoting tumorigenesis [4]

Considerable progress has been made toward developing new drugs for ferroptosis, utilizing the well-known targets of the pathological conditions (160, 161)

As expected from our previous experiments, the P44A mutant precipitated slower than the WT in the presence of EGCG, although the effect was not as pronounced as in the solid-state NMR experiments reported above

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doi: 10.1016/j.immuni.2022.05.014

These cyanobacterial toxins are reported to cause death by liver haemorrhage within a few hours of the acute doses in mouse bioassays [160]