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(37552484) Risks of high-dose acetylcysteine Case reports describe toxicity (including hemolysis and cerebral edema) following dosing errors resulting in excessive administration of acetylcysteine (e.g., 5-fold increase in the first dose, or 10-fold increase in the maintenance doses)

Meanwhile, the worm burden in the SjTGR RNAi and SjTRP14 RNAi groups were significantly reduced (Figs 6D, S12A-S12B), indicating they are essential for the schistosomes survival

1, Supplementary Fig

[170] reported that in HO-1-overexpressing MSCs, Nrf2 and HO-1 synergistically inhibit the TLR4/MyD88 pathway, reduce the release of pro-inflammatory cytokines (TNF-, IL-1), and promote macrophage polarization toward the anti-inflammatory M2 phenotype

H.MariottiC.et al (2021)

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