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1 The observed beneficial effects were obtained within the specifically overstimulated or damaged dopaminergic, serotoninergic, GABAergic and opioid systems

For reference data, see the peptide half-life chart

Under the generation of ROS and increased oxidative stress with or without inhibition of the antioxidative glutathione system of the substantia nigra, PQ elicits mitochondrial dysfunction and injury, and eventually causes neurons to embark on cell death mechanisms (Yang and Tiffany-Castiglioni, 2005

ESR, erythrocyte sedimentation rate

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Planta 180:603612 Hooper CM, Castleden IR, Tanz SK et al (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations