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Third, and perhaps most relevant, it promotes fibroblast migration and collagen synthesis , the exact cellular processes needed to rebuild the damaged annulus fibrosus

Recent studies have shown that deletion of mitochondrial pyruvate carriers in cancer cells disrupts this balance, reducing GSH synthesis and negatively impacting cell proliferation 168

doi:10.1016/j.drugalcdep.2004.03.010

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Anti-inflammatory effects of benfotiamine are mediated through the regulation of the arachidonic acid pathway in macrophages

Am J Stem Cell