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In scientific literature, senolytic strategies are also explored in models of age-related diseases where senescence is implicated, such as fibrosis, osteoarthritis, metabolic dysfunction, vascular aging, and certain therapy-induced senescence settings

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2017 Apr 6 [cited

10.1186/147268821426 193 WangX.ChangX.ZhanH.LiC.SunY.LiS.et al (2021b)

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Enhanced CHOLESTEROL biosynthesis promotes breast cancer metastasis via modulating CCDC25 expression and neutrophil extracellular traps formation

Moreover, pretreated cells displayed higher basal GCLC levels than cells without pretreatment, and the second NFT treatment led to a relatively modest additional increase (Fig