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ACSL4 is responsible for esterifying PUFAs into their corresponding acyl-CoA derivatives, after which LPCAT3 catalyzes the incorporation of these activated PUFAs into membrane phospholipids to form phospholipid-containing polyunsaturated fatty acids (PL-PUFAs) (14)

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DSIP is a neuropeptide reference compound investigated in sleep, stress, endocrine and CNS-response research