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Nasal biotransformation of xenobiotics has been addressed in the literature as many biotransformation enzymes including cytochrome P450 1B1 and glutathione S transferase P1 have been detected in nasal mucosa of humans in levels at least as abundant as in the liver [63]

Additionally, JAK3 and STAT5B mutations impair Foxp3 expression, disrupting regulatory T cell (Treg)-mediated immune tolerance

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10.1080/21505594.2018.1482181 Virulence 22 DolanS

Stem cell vectors in development In the application of stem cell transplantation, not only do the growth and differentiation degree of transplanted cells affect the therapeutic effect, but also the leakage of stem cells at the implantation site hinders the development of stem cells