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Although most research on cucumber trichomes has focused on the fruit, type I and VI trichomes can also be found on leaves, stems, flowers, and tendrils 18,19

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In a Danish cohort of patients with inflammatory bowel disease receiving infliximab, infusion reactions were most strongly associated with younger patients and with episodic therapy

For example, a recent report suggested an accelerating effect for the reaction of peroxiredoxins (Prx) with peroxides via a shift of H-bonds from the thiolate to the substrate to increase the nucleophilicity of the thiolate (33)

Further clinical studies are still lacking, most of the underlying mechanisms have been reported in animal models and need to be demonstrated for their pharmacological application

Immunol 198(12):457580 [DOI] [PMC free article] [PubMed] [Google Scholar] 42.Takada K, Jameson SC