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Moreover, ferroptosis in VSMCs is governed by multi-level regulatory mechanisms

The mode of intracellular self-digestion identified as autophagy breaks down and recycles intracellular components by encasing intracellular material in autophagic vesicles and fusing with lysosomes (Li et al., 2023)

Flavonoid 4,4-dimethoxychalcone selectively eliminates senescent cells via activating ferritinophagy

Dodd S, Dean O, Copolov DL, Malhi GS, Berk M (2008) N-acetylcysteine for antioxidant therapy: pharmacology and clinical utility

The released Glu bound to GLRs locating on the surface of the phloem cells, and then triggered an increase in [Ca 2+ ] cyt , thus propagating long-distance, Ca 2+ -based defense response, and even spreading over the whole plant body