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The cleaved N-terminal fragment of GSDME forms pores in the cell membrane, triggering pyroptosis, which is characterized by cell swelling, rupture, and the release of pro-inflammatory signals

By highlighting disparities in access to care, regional differences in survival outcomes, and the importance of early diagnosis and treatment, the study emphasizes the need for targeted interventions to reduce inequalities

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Neurosteroid pregnenolone induces sleep-EEG changes in man compatible with inverse agonistic GABAA-receptor modulation

*Correspondence: Sharmistha Dey, [email protected] ORCID: Sharmistha Dey, orcid.org/0000-0003-4122-7415 Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Tordesillas, L., Rahman, A