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Chembiochem 2025 , e202401086 (2025)

Artesunate is preferred over parenteral quinine for severe malaria treatment

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For example, T cell activation upregulates a variety of amino acid transporters, including SLC7A5, and deletion of SLC7A5 leads to activation of the mTOR signaling pathway and upregulation of the transcription factor MYC to inhibit T cell proliferation