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22 The 24h urinary copper excretion while on medication, or in patients on Dpenicillamine or trientine after a temporary period (48 h) off drug, should be measured yearly and more frequently if there are questions regarding adherence or if the medication dosage is adjusted

Not only does Vitamin B12 contribute to metabolism, helping the body create and use energy and also maintain a healthy weight, but it also is a vital player in the nervous system contributing to the creation of red blood cells and the replication of DNA

Iron can also collaborate with ROS-producing enzymes, such as NADPH oxidases (NOXs), xanthine oxidases, lipoxygenases (LOXs), and cytochrome P450 enzymes to promote the production of intracellular ROS [61]

For ( E , F ), control PBMCs or NK cell-depleted (NK) PBMCs from ATB patients were transplanted to NCG mice ( n = 6 per group)

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Reported side effects are rare and mild