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Erinacine A attenuates glutamate transporter 1 downregulation and protects against ischemic brain injury

Front Mol Neurosci 15:1007889

According to Bellikci-Koyu et al

Activation of mast cells releases histamine and mast cell proteases that may also damage intestinal barrier

(2007) further supported the role of -tocotrienol in the modulation of phospholipase A2 activities and 12-lipoxygenase, which are involved in glutamate-induced neuronal cell death