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Este defecto conlleva un bloqueo en la conversin que deriva en la acumulacin de cido metilmalnico (MMA), un producto del proceso responsable de los efectos neurolgicos que pueden empezar a aparecer en un momento determinado

Brain 138:25712583 Cramer SP, Simonsen H, Frederiksen JL, Rostrup E, Larsson HB (2014) Abnormal blood-brain barrier permeability in normal appearing white matter in multiple sclerosis investigated by MRI

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