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High levels of ROS, excessive inflammatory cells and cytokines in the wound microenvironment, insufficient new blood vessels, and weakened cell proliferation are the key factors that lead to the difficult healing of diabetic wounds 24

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(Some have theoretical worries that, for instance, BPC-157 might promote the growth of tumor cells.) On the other is an increasingly large and vocal cohort of experts and regular people who feel that the FDA, the pharmaceutical industry, and esteemed scientific institutions are gatekeeping potentially miraculous substances

There is, however, a synthetic analog of TH4 called TB-500, which has been investigated as a treatment for neurodegenerative conditions like multiple sclerosis, but its use is still largely experimental [4]

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