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Recent studies have shown that, in mammalian cells, most of the activesite disulphides in the ER oxidoreductases are reduced under normal steadystate conditions (Jessop & Bulleid, 2004)

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GLP-1 is secreted by intestinal L-cells in response to food intake and promotes insulin secretion from pancreatic -cells, thereby playing a key role in regulating the blood glucose concentration 20,21,22,23

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I've seen it in high-intensity interval training, endurance training

However, oral supplementation of L-arginine, the precursor for NO synthesis, has been shown to be largely ineffective at increasing NO synthesis and/or bioavailability for several reasons, which makes L-citrulline much more ideal for boosting levels of L-arginine and subsequently NO