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Disclosures: Jiwon Yang: Nothing to Disclose, Sun Young Yim: Nothing to Disclose, Kunhee Kim: Nothing to Disclose, Hye Won Lee: Nothing to Disclose, Jonggi Choi: GILEAD SCIENCE: Grant/Research Support 2389 BIOMARKERS ASSOCIATE WITH FIBROSIS PROGRESSION IN PATIENTS WITH PRIMARY SCLEROSING CHOLANGITIS: AN AD-HOC ANALYSIS FROM THE PRIMIS STUDY Michael Trauner 1 Kaiyi Zhu 2 Jun Xu 3 Xiangyu Liu 4 Xiaomin Lu 5 Sharlene Lim 4 Vlad Malkov 4 William Barchuk 4 Lisa Boyette 5 Zachary Goodman 6 Atsushi Tanaka 7 Douglas Thorburn 8 Cynthia Levy 9 Christopher Bowlus 10 , 1 Medical University of Vienna, 2 Gilead Sciences Inc, 3 Gilead Sciences, Inc., 4 Gilead Sciences Inc., 5 Gilead Sciences, 6 Inova, 7 Teikyo University School of Medicine, 8 Royal Free Hospital, 9 University of Miami, 10 University of California, Davis Background and Aim: Primary sclerosing cholangitis is a chronic progressive liver disease characterized by biliary inflammation and fibrosis

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