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Samples were mixed with 10 native loading buffer (1.5 M Aminocaproic acid, 50 mM Bis-Tris, 0.5 mM, EDTA, 5% (w/v) Serva Blue G, pH 7.0) and electrophoresed on 310% self-cast gels

Funding This work was supported by the Natural Science Foundation of China (81803045, 82103277), the China Postdoctoral Science Foundation (2020M672072), the Research Project of Jinan Microecological Biomedicine Shandong Laboratory (JNL-2022041C), Shandong Excellent Young Scientists Fund Program (2022HWYQ-035), Shandong Provincial Natural Science Foundation (ZR2021QH030), and the Qilu Young Scholar Program of Shandong University, China