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Rucaparib monotherapy in the heavily pre-treated metastatic castrate-resistant prostate cancer setting: practical considerations and alternate treatment approaches

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[47] demonstrated that in mammalian cells, HIF-1 reciprocally controlled cytochrome c oxidase 4 (COX4) subunit expression under circumstances of low O 2 availability by promoting transcription of the genes encoding COX4-2 and LON, a mitochondrial protease necessary for COX1-1 breakdown

Dai, CBG-CS-2 strain, isolated from Cordyceps spp