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Total plasma antioxidant activity was determined through total antioxidant status (TAS) measurement (mmol/L) (Randox Laboratories, UK)

( F ) Ex vivo 15LO1 protein expression correlates with intraepithelial cell GSH and GSH:GSSG ( n = 15)

Specific knockdown of LDHA using SiRNA significantly reduces intracellular HMGB1 levels and prevents pyroptosis [113]

Phagocytes primarily function in phagocytosis, which involves the engulfment and digestion of cell debris and pathogens, either as fixed or free-floating cells