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The scarcity of studies on gut microbiota changes and microbiome-based interventions in HD may be related to the existence of other research priorities, such as the development of genetic treatments, and the lower prevalence of HD compared to other conditions

Unlike many other peptides where timing is merely a convenience factor, MOTS-c timing directly impacts its mechanism of action

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Most studies were cross-sectional, which reduced the ability to make causal inferences as well as generalize the findings to the broader community

Detoxification pathway support*

Oct 2010;19(7):1193-200