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After excluding cases who had died of non-atherosclerotic CVDs (n = 13), the association between GPx3 activity and cardiovascular mortality in those with below median HDLcs remained essentially the same compared to those in the lowest GPx3 quartile

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Hesperidin activates Nrf2 to protect cochlear hair cells from cisplatin-induced damage

82 Noncanonical pathway In lung homogenates from Fra-2 transgenic mice, upregulation of TGF- leads to increased JUN-B expression and binding of the AP-1 complex to the meprin promoter, resulting in elevated meprin expression

Moreover, the NF-B p52 functions in Th17 cells to mediate production of the proinflammatory cytokine GM-CSF, which is required for second wave of immune cell recruitment to the CNS and EAE pathogenesis [63] (Fig

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