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Recent studies looking at the telomeric proteome during replication observed high levels of histone protein H1 at telomeres during replication (Lin et al 2021), and cells that had H1 depleted through knockout experiments are sensitive to DNA damage and double strand breaks (Murga et al 2007)

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The peptide's anti-inflammatory effects complement its synaptogenic properties, as chronic neuroinflammation actively disrupts synaptic function and prevents formation of new synapses

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Glutathione modulates cell-mediated immune responses like macrophage activity, T-cell proliferation, and NK (natural killer) cell activity in maternal tissues

Clinical research in older humans confirms these mechanisms translate to human aging