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2e,f) and fewer CD68 + macrophages in distant tissues (Extended Data Fig

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It is used to treat age-related macular degeneration, impaired vision, allergies, retinitis pigmentosa, dry eye, and cataracts

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Assuming a continuous bleed system that is 100% effective, thus for this system, the minimum makeup water requirement is: Evaporation + Drift + Blowdown = 0.442kg/s + 0.0239kg/s + 0.0645kg/s = 0.53kg/s As the density of water is approximately 998 kg/m3 at sea level and habitable outdoor temperatures, or ~1 kg/L, this would be 0.53 L/s for make-up water

(1992a)