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These results highlight a novel intestinal mechanism underlying metformins efficacy and provide insights for potential therapeutic strategies beyond traditional glucose regulation

Mesoporous silica nanoparticle based nano drug delivery systems: synthesis, controlled drug release and delivery, pharmacokinetics and biocompatibility

& Kyriakides, T

Kreitman and Pastan (1993) Bioconjug

5 (Ci 19140), Fd&Amp;C Yellow No

Research applications Research applications Investigation of FOXO4p53 interaction disruption and downstream apoptotic signaling In vitro studies of cellular senescence, senolysis, and age-related cell clearance Combination studies with chemotherapeutics, targeted agents, or senolytic compounds Mechanistic assays of apoptosis markers, mitochondrial dysfunction, and cell viability For laboratory research use only