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High-dose ubiquinol supplementation in multiple-system atrophy: a multicentre, randomised, double-blinded, placebo-controlled phase 2 trial

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Ultracentrifugation, widely regarded as the gold standard, often co-isolates contaminating proteins, small microvesicles, and apoptotic bodies, leading to heterogeneous preparations with variable purity [133-134]

In oxidative stress, D-LDH seems the most promising candidate gene for providing tolerance

Regular monitoring of ferritin levels may also provide additional benefits in evaluating progression to cirrhosis and HCC and in determining the need for liver biopsy [205]