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J Biol Chem 284:56375644

Carnitine has been reported to exert a beneficial effect on synaptic plasticity through a range of mechanisms, including its antioxidant and anti-inflammatory effects, as well as its capacity to regulate the expression of synaptic plasticity-related biomarkers [100,101,102]

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Interestingly, the pharmacological inhibition of GSK-3 by lithium activates NrF2, providing plausibility for certain aspects of lithiums mechanism of action to occur through ferroptosis inhibition through the GSK-3/ NrF2 pathway [173]

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