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The use of the nomogram should be avoided until 4 h or more after ingestion as the levels may be misleading during this timeframe from the point of acute ingestion and not be an accurate predictor of toxicity[64,65]

Recently, our group found that substitution of Ser for Cys would not cause dramatic loss of GPx activity compared to changing those Cys to Sec 15,16

2019JJ40238), the Defense Industrial Technology Development Program (no

The doses were chosen in order to monitor autoprotection across a range of sub-toxic, threshold toxic and overtly toxic doses of APAP, to ensure that the drug exposure is relevant to what may occur in humans

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GSH and neurodegeneration The brain is particularly vulnerable to oxidative stress due to relatively lower antioxidant enzyme activities (SOD, GPx, GR and catalase) compared to other tissues