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Accumulated ROS can damage mitochondrial and nuclear DNA, proteins and lipids, further impairing cellular function and viability (Khan et al

8 Another portion of APAP (10%) is shunted by hepatic cytochrome CYP 2E1 (to a lesser extent with CYP 1A2 and 3A4) to phase I oxidation, in which a highly reactive toxic metabolite, N -acetyl-para-benzo-quinone imine (NAPQI), is formed

Minerals are depleted in times of stress, and also in the case of hyperthyroidism, given that the body is using a tremendous amount of resources to keep up with thyroid overactivity

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Vitamin B12 has been shown to alleviate symptoms of peripheral neuropathy, particularly when the condition is related to a B12 deficiency

Jin Y, Qiu J, Lu X, Li G