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To unequivocally establish ozone therapy standing as an efficacious knee OA treatment, there is an undeniable need for comprehensive, multicentre RCTs with extended follow-ups to corroborate its long-term benefits and reliability

Multiplexing is the practice of recognizing numerous biomarkers in one diagnostic test to statistically improve detection accuracy

Everywhere else, for patient data, two-sided paired t tests were carried out, while for in vitro data, it was subjected to unpaired two-sided Student t tests, always with a p value of 0.05 as the cutoff for significance

Glutathione is a natural antioxidant that helps fight free radicals, scavenges the body of harmful bacteria and toxins, and boosts immunity, among other effects, and has been closely linked to a variety of diseases

Subsequently, the respective reagents from the OCR and ECAR assay kits were added to the cells

[168]. David C