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Gene expression is regulated by these changes, which affect whether genes are in an active, transcription-friendly state or a silent, repressive state [192]

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Androgen insensitivity syndrome Differences of sex development condition characterized by decreased or absent androgen signalling due to a genetic defect affecting the binding of testosterone or dihydrotestosterone to the androgen receptor

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It may neutralise free radicals that cause oxidative stress and skin damage

Spiking experiments involved addition of known amounts of pure NAD and glutathione compounds individually at different stages of the extraction (Supplementary Table 1), followed by quantification using colorimetric assays