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Authors contributions PGE y RRF conceived of the study and participated in its design

[1] [3] For context, cold sensations have been reported anecdotally by some users of approved GLP-1-based therapies such as semaglutide (Wegovy, Ozempic)

However, it does reinforce that the program's long-term financing challenge has become larger, driven primarily by demographic trends, with a smaller assist from recent tax policy

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